The experiment on “Effect of organic manures on growth yield and nutrient uptake of Plectranthus vettiveroides was carried out in Kollidam during 2020-2022. A field trial was conducted in a Randomized Block Design with nine treatments in three replications. The treatment consisted of organic manures at farmyard manure, vermicompost, neem cake and groundnut cake. Among the different treatments, application of (Vermicompost @ 5 t ha-1 + Groundnut cake @ 200 kg ha-1 + Azospirillum @ 2 kg ha-1) resulted in enhancing the growth characters like plant height, number of branches per plant, stem girth, number of leaves per plant when compared to control. The number of primary and secondary roots, root length, volume of roots showed an increasing trend at different stages of evaluation and the treatment (Vermicompost @ 5 t ha-1 + Groundnut cake @ 200 kg ha-1 + Azospirillum @ 2 kg ha-1) recorded the highest root numbers, root length, and girth. Application of (Vermicompost @ 5 t ha-1 + Groundnut cake @ 200 kg ha-1 + Azospirillum @ 2 kg ha-1) was found to influence the chlorophyll content index of leaves and root oil content. Based on findings of the present study it can be concluded that present study it can be concluded that combination application of (Vermicompost @ 5 t ha-1 + Groundnut cake @ 200 kg ha-1 + Azospirillum @ 2 kg ha-1) was found to be beneficial for increasing the growth and Physiological parameters of Plectranthus vettiveroides