The present study was aimed to determine the contents of vitamins (thiamine, riboflavin and ascorbic acid) and minerals (K, P, Zn, Cu, Zn, Mn, Ca and Fe) in cultivated mushrooms viz. Agaricus bisporus and Pleurotus sajor caju. Both Agaricus bisporus and Pleurotus sajor caju mushroom were found to be an excellent source of potassium and phosphorus. The contents of K, P, Ca, Zn and Fe in Agaricus bisporus was 4015, 1350, 47 and 13.23 mg/100g dry weight respectively, whereas in Pleurotus sajor caju mushroom the contents of K, P, ca and Zn was found to be 3218, 1246, 73 and 12.77 mg/100 dry weight, respectively. However, comparison of both the mushrooms revealed that Agaricus bisporus mushroom contained significantly higher amount of phosphorus, potassium, zinc, copper and manganese and lower amount of calcium and iron as compared to Pleurotus sajor caju mushroom. Both the mushrooms contained good amount of water-soluble vitamins namely, thiamine, riboflavin and ascorbic acid. The amount of ascorbic acid (4.43%) was almost double in Pleurotus sajor caju as compared to Agaricus bisporus mushroom (2.25%).