Somatic cells are leukocytes and epithelial cells from blood and gland. The somatic cell count increases when the cow has mastitis infection as the leukocytes in the blood increases to fight against the infection.so in this research we have concluded that, which quality parameter increases and decreases. We have studied increasing parameters such as ph, conductivity, MBRT time, and decreasing parameters such as protein%, fats%, lactose%, caesin%, snf%, and detection of antibiotics was done with the help of Delvotest SP NT DA kit. Mastitis in cow can alter the physical, chemical and bacteriological properties of milk which leads to low quality milk and according to animals this disease, decreases the life of animal. This article highlights the change in nutrient composition of milk with respect to increasing somatic cell count.