Background & Objectives: Polycystic Ovarian Syndrome (PCOS) occurs among females of reproductive age and prevalence ranges from 3.7 to 22 per cent in Indian women. As weight management is recommended as one of the first line of treatment for PCOS, the present study was conducted to assess the impact of weight loss and improvement of selected symptoms of PCOS clients enrolled in Truweight program. Materials & Methods: This was a six months observational study among known PCOS females enrolled in the Truweight program between the ages of 17 to 40 years, BMI > 30kg/m2 were selected using purposive sampling technique. Initial and final data were collected in terms of weight, BMI, nutrient intakes, and selected symptoms. Initial and final readings were recorded and the data was analysed using suitable statistical techniques. Results: There was a significant reduction in BMI (35.28± 5.79 to 30.65 ±5.56) after following Truweight program. The per cent weight loss was between 8 to 20 percent of their initial body weight. Major PCOS symptoms like Irregular cycles (84 per cent), Facial hair (54 per cent) and Acne (32 per cent) have shown improvement. The mean macronutrient intakes such as carbohydrate (154.38g), protein (46.22g) and fat (25g) were positively correlated with weight loss. Conclusion: The present study concludes that diet management is key to significant reduction in BMI and help improving the PCOS condition and the symptoms associated.