Flaxseed oil intake in post weaning period contributes to bone health of lactating rats
Carolina Ribeiro Pessanha, Bianca Ferolla da Camara Boueri, Aline D' Avila Pereira, Danielle Cavalcante Ribeiro, Gilson Teles Boaventura, Carlos Alberto Soares da Costa
The aim of this study was to evaluate the effect of flaxseed oil on the composition and bone quality of lactating Wistar rats in the postweaning. Wistar rats females were randomly separated into control (C) and experimental (OL) groups. Group C received a control diet, during the 21-day lactation period and during 30 days after weaning. The OL group, as group C, continued the same period of study, however receiving an experimental diet with flaxseed oil in the composition. The end of the experiment, the animals were anesthetized, and were evaluated the bone composition through Dual-energy X-ray absorptiometry (DXA) and after, euthanasia was done. The femurs were collected for the analysis of bone composition by DXA, analysis of bone dimensions, computed tomography and biomechanical test. Higher values were found in the OL group in relation to total bone mineral content, serum calcium, bone mineral density of the femur, femoral mass, distance between the epiphyses and distance at the midpoint of the diaphysis of femurs. In the biomechanical test and tomography, higher values were found in the OL group when compared whit C group. In conclusion, fatty acid composition of flaxseed oil was able to promote positive effects in bone composition of female’s rats in the post weaning period.