This study investigated the impact of the harvest period on some agronomic parameters of the tuberous roots of yacé cassava variety. Fresh weight, number, length, girth, state, and yield per roots block based on harvest period (11th, 12th, 13th and 14th months after planting) were determined. The roots state (good or rotten) and roots number are not influenced by the harvest period. The roots number ranged from 6.4 to 6.8 from the eleventh to the fourteenth month of harvest. However, the highest yield was obtained at the fourteenth month of harvest after the cuttings were planted (20.46 tons / ha). Also, cassava cuttings harvested in the fourteenth month showed maximum fresh weight (1.02 Kg), length (39.38 cm), and circumference (24.15 cm).