A review article on impact of drug food interactions and its prevention
Dr. Ruth Rajan, Dr. Arpan Dutta Roy, Dr. SK Todi, Dr. Pinaki Dutta, Dr. TK Chatterjee5, Dr. Sudeshna Lahiri, Dr. Abhijit Sengupta
A drug food interaction is a condition in which a substance effects the activity of a drug and the effects are increased or decreased or they produce a new effect that neither produces on its own. This may occur out of accidental or due to lack of knowledge about the interactions. The main aim of the review is to access a potential impact of drug food interaction. Moreover common use of medications continues to grow drug food interaction. In this review, we have mentioned about the basic information and its importance with common specific examples of both food and drug.It is well acknowledged and identified that drug food interaction occurs. Many medicines have a potent ingredients that interacts with food within a human body in different ways. Diet and lifestyle sometimes have a significant impact on drugs. At present, natural foods and vegetal supplements have recently become gradually popular of their roles. The consumption of foods and vegetal supplements has increased spectacularly over the last few decades raising concerns over the potential interaction between foods products and drugs in patient undergoing therapy. Some commonly used herbs, fruits as well as alcohol may cause therapy failure thus causes changes in the bioavailability of drugs. In addition, some people have a greater risk of food and drug interaction who have poor diet, serious health problem, elderly patients, children and pregnant women. Sometimes interaction may takes to the benefits of patients, but most commonly it results in adverse drug events. Therefore it is advisable to patients and caregiver to get instruction from the physicians and clinical pharmacists to obtain maximum benefits with least drug food interaction. This review gives common information to doctors, clinical pharmacists and other health-care providers about various interactions between drugs and foods. This will help to prescribe drug cautiously with time intervals between the drugs and foods or suitable supplements to get maximum benefits for the patients.