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VOL. 7, ISSUE 3 (2022)
The relationship between probiotics and digestive health: A critical mechanism of gastrointestinal neuromodulation and immunomodulation
Authors
Chandan Samanta, Souvik Tewari, Debnanda Chakraborty
Abstract
The term "gastrointestinal microbiota" refers to the microbial population in the gastrointestinal system. The gastrointestinal tract contains 3.8 × 1013 microorganisms, most of which carry out their primary functions here. The gastrointestinal microbiota family known as probiotic bacteria is administered orally from the outside environment through food. Probiotics function in a variety of ways in the digestive system. Probiotics contribute to an expansion of the prebiotic bacterial ecosystem in the gastrointestinal tract, which aids in the digestion and absorption of undigested long-chain polysaccharides. Their primary function is to ferment those foods and create short-chain fatty acids, which have a favourable effect on pancreatic output and epithelial cell growth. Probiotics minimise damage to the intestinal host cell, lessen inflammation, and restrict the host immune response by producing the cytokines interleukin-10 and interleukin-12. These have the ability to modulate immune cell activity and cause T cells and B cells to become less sensitive. Probiotic bacteria can influence the digestive tract's immune system in this way. Probiotic bacteria can occasionally keep the neuronal connection between the central nervous system and the gastrointestinal tract functioning. Probiotics aid in the submission and transmission of neural impulses between the central nervous system and the gastrointestinal tract. Numerous studies have shown that probiotics may boost brain function and reduce anxiety and depressive symptoms.
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Pages:162-169
How to cite this article:
Chandan Samanta, Souvik Tewari, Debnanda Chakraborty "The relationship between probiotics and digestive health: A critical mechanism of gastrointestinal neuromodulation and immunomodulation". International Journal of Food Science and Nutrition, Vol 7, Issue 3, 2022, Pages 162-169
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