Vol. 3, Issue 5 (2018)
Cardio protective activity of Abelmoschus esculentus (Okra)
Author(s): Vindika Sumudunie Kuruwitaarachchige, Deepthi Inoka Uluwaduge, Sirimal Premakumara, Jayantha Wijayabandara
Abstract: Okra or Lady’s fingers (Abelmoschus esculentus) is a popular vegetable of the Malvaceae family. Several pharmaceutical benefits of okra fruit have been documented. This study investigated the effect of mucilage of okra (crude water extract and water fraction) fruit on lipid parameters in a high- fat diet fed rats. Okra crude water extract (500 and 1000 mg/kg body weight) or water fraction (50 and 100 mg/kg body weight) was provided with a high fat diet to hypercholesterolemic rats for one week. The effect of treatment of okra fruit on lipid parameters of hypercholesterolemic rats were evaluated and compared with the negative control and positive control rats. Crude water extract (1000 mg) and the water fraction of okra (50 mg and 100 mg) had the potential to reduce (p< 0.01) different lipid fractions (total cholesterol, triglycerides, LDL and VLDL) and atherogenic index in the test group. The mucilage had the potential to increase the HDL fraction (p< 0.01) of the test group. These results suggest that crude water extract and the water fraction of the okra fruit modulate the blood lipid levels favorably and have the potential to be used as a “heart friendly” vegetable.